MARS 6 Synthesis

Parallel & Scale-Up Microwave Synthesizer

THIS PAGE INTENTIONALLY LEFT BLANK

Contents

Safety

Safety Notations 1

Introduction

About the Instrument 2

Back and Side View 6

Cavity 7

Software Overview

Software Icons 8

Home Screen 9

Methods Screen (One Touch and Classic) 9

System Menu 10

System Installation

Unboxing 13

System Setup 15

Create a One Touch Method 22

Edit Method 22

Delete Method 22

Export Method 23

Import Method 24

Edit/Delete User 26

Auto Login 26

Password Conguration 27

Data Management

Temperature Calibration (IR Sensors) 31

Pressure Calibration 32

Power Test

Power Test 33

Printer (Optional)

Internal Printer 34

Fiber Optic Temperature Control

Fiber Optic Installation 35

Fiber Optic Temperature Verication 36

Fiber Optic Care 37

Annually 39

As Needed 39

Troubleshooting

Problems and Possible Solutions 40

System Specifications

Location Requirements 41

Electrical Requirements 41

Environmental Requirements 41

Warranty

Limited Warranty Information 42

Appendix B: EasyPrep and EasyPrep Plus Vessels

Vessel Components 54

Operating Parameters 55

New Liner and Cover Conditioning 55

Perform a Reaction 56

Vessel Cleaning 65

Appendix C: Open Vessel Reactions

Vessel Components 67

Operating Parameters 67

Perform a Reaction 68

CEM Corporation Headquarters 73

CEM International Subsidiaries 73

CEM Distributors 74

Safety

Safety Notations

This manual uses three safety alert words at points in the documentation where the user should be aware of

potential hazards. The safety alerts are shown in color-coded boxes. The three words – NOTE, CAUTION, and

WARNING – indicate differing levels of observation or action as described below:

A WARNING is intended to emphasize dangerous or hazardous conditions that may result in personal

injury to the user and/or damage or destruction of the instrument.

About the Instrument

The MARS™ 6 Synthesis is a multi-mode microwave system that provides parallel reaction processing, under

uniform conditions. The power output on this particular system is programmable up to 1800 watts and uses an

advanced feedback system to monitor and control the rate of heating of the sample(s) in the cavity. The MARS 6

Synthesis Open Vessel Option includes an I/O Port located in the top center of the microwave cavity. This opening

permits the attachment of a reux condenser to the reaction vessel inside the microwave cavity. Any type of round

bottom ask may be used with the system with volumes ranging from 250 mL to 5 L. The sample stirrer is a

rotating magnetic eld in the bottom of the instrument which works in conjunction with stirring bars placed in the

vessel liners to ensure a homogeneous sample.

The MARS 6 Synthesis is designed to be operated in accordance with the guidelines outlined in this manual.

The GlassChem, EasyPrep™, and EasyPrep Plus™ are the only approved sealed vessels designed for synthetic

Important Safeguards

General guidelines for safe operation of the MARS 6 Synthesis system are presented below and all specic safety

messages are located throughout the manual.

Proper precautions must be taken to avoid contact with reagents or reagent vapors. Protective gear should be worn

as outlined in the user’s safety program for hazardous materials and the reagent manufacturer’s safety data sheet.

Refer to these guidelines for proper handling and disposal of the reagents. Dispose of all waste in accordance with

all applicable local, state, and federal health and safety recommendations.

Solvent Chart

The below chart provides some representative examples of microwave absorptive properties for a variety of

common synthetic solvents. For solvents not included in this chart, contact your CEM representative.

A minimum cavity load must be met before running a microwave method. The minimum cavity load is determined

by the solvent, number of vessels, and vessel type: GlassChem 20, EasyPrep, EasyPrep Plus, and Open Vessel.

Microwave Safeguards

• Never heat liquids in a sealed vessel or container that is not equipped with a pressure relief device.

• Cover all solids in the reaction vessel with liquid

Instrument Overview

Instrument Overview

Front and Side View

System Installation

Unboxing

1. View the Site Preparation Guide (P/N FM0050) and select a location that meets requirements before installing

ing handles.

4. Use top handles to pull up and remove outer box.

5. Carefully cut the tape on both sides of the inner box.

14 System Installation

6. Lay the sides of the box at and remove the foam from the top of the system.

7. Lift the system, from the sides, onto bench top near exhaust service (two people required). Do not place the

system in a fume hood.

8. Remove the plastic and discard. Do not leave the plastic under the system.

3. Plug power cord into the system and a dedicated, grounded outlet. The instrument is supplied with a power

cord, but an adequately rated power cord may be used.

16 System Installation

4. Position the instrument so the door is facing forward and so there is open space to access the power switch.

5. Locate the power switch on the right side of the instrument, and position it in the ON position.

6. When the system is rst powered on during the install, a “Line Voltage” message will appear.

7. Determine the line voltage from outlet:

• 60 Hz, 208 V or 230 V

• 50 Hz, 200 V, 220 V, or 240 V

8. Set the line voltage.