Roche cobas s 201 system User manual

Brand: Roche

Model: cobas s 201 system

Type: User manual

Roche cobas s 201 system is a fully automated molecular diagnostics system that combines sample preparation, amplification, and detection into a single, easy-to-use platform. The system is designed for use in clinical laboratories and can be used for a variety of applications, including infectious disease testing, genetic testing, and oncology testing. The cobas s 201 system is capable of processing up to 96 samples per run and provides results in as little as 3 hours. The system is also easy to use, with a simple touchscreen interface and intuitive software.

05/2008, version 1.0 2.1

Docking Station 2

Overview

The Docking Station (Figure 2.2) connects the COBAS

AmpliPrep

Instrument to the COBAS

TaqMan

Analyzer and fully automates sample

preparation, amplification, and detection.

When the Docking Station is installed, prepared K-tubes are automatically

transferred from the COBAS

AmpliPrep Instrument to the COBAS

TaqMan

Analyzer as shown in Figure 2.2.

Figure 2.1

Docking Station

Figure 2.2

Overview of the cobas s 201 system with Docking Station

2.2 05/2008, version 1.0

Installation

Transportation and Storage Conditions

The Docking Station is transported in a palletized container.

The Docking Station weight, including accessories, pallet and packaging

materials, is approximately 35 kg (77 lb).

Docking Station Dimensions and Weight

Unpacking and Installation

The original shipping container must be transferred unopened to the

installation site. The Docking Station should be unpacked and installed by

trained Roche Service personnel. No attempt should be made by the user

to remove, set up, or operate the instrument without Roche Service

personnel being present.

The packing list that accompanies the Docking Station contains the

description, part number, and quantity of all component parts,

accessories, and consumables delivered with the instrument. This packing

list should be verified against the delivered items and retained for future

reference.

Electrical Power Requirements

The Docking Station is designed in accordance with EN/IEC 61010-1,

EN/IEC 61010-2-101, UL 61010A-1, and CAN/CSA C22.2 No. 1010.1.

Environmental Requirements

The Docking Station is designed for indoor use at an altitude below 2,000

meters (6,500 feet). Room temperature should be between 15° C to 32° C

(59° F to 89° F), and relative humidity should not exceed 80% at 32° C

(89°

F) without condensation. Atmospheric conditions should conform to

Pollution Degree 2 (according to EN/IEC 61010-1).

Width 35 cm (13.75 in)

Depth 43 cm (17 in)

Height 76.5 cm (30 in)

Weig ht 25 kg (55 lb)

Docking Station

power consumption

typically 30 VA

maximum 90 VA

Docking Station

05/2008, version 1.0 2.3

Methodology

The Docking Station links a COBAS

AmpliPrep Instrument to a COBAS

TaqMan

Analyzer (Figure 2.3) and fully automates sample handling

during sample preparation, amplification, and detection.

When preparation of each sample is completed, the K-tube containing the

prepared sample is automatically placed in a K-carrier. When sample

preparation of a batch is completed, the loaded K-carrier is then

automatically loaded onto the Docking Station multicarrier (

Figure 2.4)

by the COBAS

AmpliPrep Instrument.

The Docking Station then transports the multicarrier containing the

K-carrier from the COBAS

AmpliPrep Instrument to the COBAS

TaqMan

Analyzer (Figure 2.4).

Figure 2.3

Docked COBAS

Ta qM an

Analyzer

Docking Station

COBAS

AmpliPrep Instrument COBAS

Taq Man

Analyzer

Figure 2.4

Transport of the K-carrier on a Multicarrier by the Docking Station

Multicarrier

K-carrier

2.4 05/2008, version 1.0

The COBAS

TaqMan

Analyzer then transfers the K-carrier from the

multicarrier to a thermal cycler (

Figure 2.5) and performs amplification

and detection on the K-tube contents. After amplification and detection is

completed, empty K-carriers are returned to the COBAS

AmpliPrep

Instrument by the Docking Station.

Figure 2.5

Unloading of the K-carrier

Docking Station

05/2008, version 1.0 2.5

Loading Empty K-carriers

When using the Docking Station, an empty K-carrier must be present in

each of the two K-carrier park positions of the COBAS

AmpliPrep

Instrument and in positions 9 to 12 of the Reload Area of the COBAS

TaqMan

Analyzer.

If empty K-carriers are not present in these positions, they must be loaded

into these positions before starting a run.

Loading Two Empty K-carriers in the K-carrier Park Positions on the COBAS

AmpliPrep Instrument

1 Turn off the instrument power switch.

2 Open the main cover.

3 Load two empty K-carriers in the two K-carrier park positions

(Figure 2.6).

4 Close the main cover.

5 Turn on the system power switch.

Figure 2.6

Location of the K-carrier Park Positions on the COBAS

AmpliPrep Instrument

K-carrier Park Positions

2.6 05/2008, version 1.0

Loading Four Empty K-carriers in the K-carrier Reload Positions on the COBAS

Ta q M a n

Analyzer

1 Turn off the instrument power switch.

2 Open the main cover.

3 Load four empty K-carriers in K-carrier reload positions 9 through 12

(Figure 2.7).

4 Close the main cover.

5 Turn on the system power switch.

Docking Station Maintenance

There are no user serviceable parts on the Docking Station.

Contact your Roche Service representative, who is trained and qualified to

perform the necessary servicing, for service.

Figure 2.7

Location of K-carrier Reload Positions 9 through 12 on the COBAS

TaqMan

Analyzer

K-carrier Reload

Positions 9 through 12

K-carrier Park Position 2

Roche cobas s 201 system User manual

Roche cobas s 201 system User manual

Roche cobas s 201 system User manual

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