Beckman Coulter Biomek NXP Preinstallation Manual

B20063AC

April 2019

Preinstallation Manual

Biomek NXP

Laboratory Automation Workstation

Beckman Coulter, Inc.

250 S. Kraemer Blvd.

Brea, CA 92821 U.S.A.

Biomek NXP Laboratory Automation Workstation

Preinstallation Manual

PN B20063AC (April 2019)

Beckman Coulter, the stylized logo, and the Beckman

Coulter product and service marks mentioned herein are

trademarks or registered trademarks of Beckman Coulter,

Inc. in the United States and other countries.

Windows 7 and Windows 10 are registered trademarks or

trademarks of Microsoft Corporation in the United States

and/or other countries.

All other trademarks, service marks, products, or services

are trademarks or registered trademarks of their

respective holders.

May be covered by one or more pat. - see

www.beckman.com/patents

Contact Us

If you have any questions, contact our Customer Support

Center.

• Worldwide, find us via our website at

www.beckman.com/support/technical

• In the USA and Canada, call us at 1-800-369-0333.

• Outside of the USA and Canada, contact your local

Beckman Coulter Representative.

Glossary of Symbols is available at

beckman.com/techdocs (PN C24689).

Original Instructions

B20063AC iii

Revision History

Initial Issue B20063AA, 05/2013

Issue AB, 03/2018

Changes or additions were made to: CHAPTER 1, Air Supply Requirements (NX-MC and NX-S8 with

a Microplate Shaking ALP only).

Issue AC, 04/2019

Changes or additions were made to: Table1.1,System Specifications; Table1.4,Electrical

Components and Requirements; Table4.1,Electrical Components and Requirements; Related

Documents.

Note: Changes that are part of the most recent revision are indicated in text by a bar in the margin of the

amended page.

This document applies to the latest software listed and higher versions. When a subsequent software

version changes the information in this document, a new issue will be released to the Beckman Coulter

website. For labeling updates, go to www.beckman.com and download the most recent manual or system

help for your instrument.

B20063AC

iv

Revision History

B20063AC v

Safety Notice

Read all product manuals and consult with Beckman Coulter-trained personnel before attempting

to operate instrument. Do not attempt to perform any procedure before carefully reading all

instructions. Always follow product labeling and manufacturer’s recommendations. If in doubt as

to how to proceed in any situation, contact your Beckman Coulter Representative.

Beckman Coulter, Inc. urges its customers to comply with all national health and safety standards

such as the use of barrier protection. This may include, but is not limited to, protective eyewear,

gloves, and suitable laboratory attire when operating or maintaining this or any other automated

laboratory analyzer.

Alerts for Danger, Warning, Caution, Important, and Note

DANGER

DANGER indicates an imminently hazardous situation which, if not avoided, will

result in death or serious injury.

WARNING

WARNING indicates a potentially hazardous situation which, if not avoided, could

result in death or serious injury.

CAUTION

CAUTION indicates a potentially hazardous situation, which, if not avoided, may

result in minor or moderate injury. It may also be used to alert against unsafe

practices.

IMPORTANT IMPORTANT is used for comments that add value to the step or procedure being performed.

Following the advice in the Important adds benefit to the performance of a piece of equipment or to a

process.

NOTE NOTE is used to call attention to notable information that should be followed during installation, use,

or servicing of this equipment.

B20063AC

vi

Safety Notice

Electrical Safety

To prevent electrically-related injuries and property damage, properly inspect all electrical

equipment prior to use and immediately report any electrical deficiencies. Contact a Beckman

Coulter Service Representative for any servicing of equipment requiring the removal of covers or

panels.

High Voltage

This symbol indicates the potential of an electrical shock hazard existing from a high-voltage

source and that all safety instructions should be read and understood before proceeding with the

installation, maintenance, and servicing of all modules.

Do not remove system covers. To avoid electrical shock, use supplied power cords only and connect

to properly grounded (three-holed) wall outlets. Do not use multiplug power strips.

B20063AC vii

Safety Notice

Warnings and Cautions Found in this Manual

Please read and observe all cautions and instructions. Remember, the most important key to safety

is to operate this instrument and its supporting equipment with care.

The WARNINGS and CAUTIONS found within this document are listed below.

WARNING

Risk of operator injury if:

• All doors, covers, and panels are not closed and secured in place prior to and

during instrument operation.

• The integrity of safety interlocks and sensors are compromised.

• Instrument alarms and error messages are not acknowledged and acted upon.

•You contact moving parts.

• Doors, covers, and panels are not opened, closed, removed, and/or replaced

with care.

• Improper tools are used for troubleshooting

To avoid injury:

• Keep doors, covers, and panels closed and secured in place while the

instrument is in use.

• Take full advantage of the safety features of the instrument. Do not defeat

safety interlocks and sensors.

• Acknowledge and act upon Instrument alarms and error messages.

• Keep away from moving parts.

• Report any broken parts to your Beckman Coulter Representative.

• Open/remove and close/replace doors, covers, and panels with care.

• Use the proper tools when troubleshooting.

CAUTION

System integrity might be compromised and operational failures might occur if:

• This equipment is used in a manner other than specified. Operate the

instrument as instructed in the Product Manuals.

• You introduce software that is not authorized by Beckman Coulter into your

computer. Only operate the computer of your system with software

authorized by Beckman Coulter.

• You install software that is not an original copyrighted version. Only use

software that is an original copyrighted version to prevent virus

contamination.

B20063AC

viii

Safety Notice

Warnings and Cautions Found in this Manual

CAUTION

If you purchased this product from anyone other than Beckman Coulter or an

authorized Beckman Coulter distributor, and if it is not presently under a Beckman

Coulter service maintenance agreement, Beckman Coulter cannot guarantee that

the product is fitted with the most current mandatory engineering revisions or

that you will receive the most current information bulletins concerning the

product. If you purchased this product from a third party and would like further

information concerning this topic, call your Beckman Coulter Representative.

WARNING

To prevent possible injury, wear safety glasses or safety goggles when removing

metal strapping. Strapping may spring back, causing injury.

WARNING

To prevent possible injury, use the steel strapping cutter with caution to ensure

the strap does not spring back.

CAUTION

When lifting the Biomek NXP instrument, grasp it only from positions on the base

casting. Do not grasp the ends of the light curtain that extend across the front of

the instrument.

CAUTION

The back of the instrument is heavier than the front. Take care not to lift the front

so high that it causes the instrument to fall backward.

CAUTION

The Biomek NXP instrument will overhang the edges of a 36 in. x 30 in. (92 cm x

77 cm) bench. Make sure there are no obstacles that will interfere with placement

of the instrument.

B20063AC ix

Safety Notice

Warnings and Cautions Found in this Manual

CAUTION

Make sure the bench can support the total installed weight of the system. Refer

to Table 1.3 to determine the total weight of the system.

CAUTION

When lifting the Biomek NXP instrument, grasp it only from positions on the base.

Do not grasp the ends of the large cover at the top of the instrument.

CAUTION

The optical table is heavy and is cumbersome. To avoid injury, two people are

needed to unpack the optical table from the shipping crate.

CAUTION

The Cytomat weighs 176 - 311 pounds. To avoid injury, follow your safety officer's

instructions regarding lifting heavy objects.

WARNING

To prevent the side panels from falling on the person unpacking a Cytomat device,

a second person must hold each panel while the screws are removed.

B20063AC

x

Safety Notice

Warnings and Cautions Found in this Manual

xi

Contents

Revision History,iii

Safety Notice,v

CHAPTER 1: Preparing the Site,1-1

Preparation Overview,1-1

Models,1-1

Site Preparation,1-1

Biomek NXP System Specifications,1-2

Work Area Minimum Dimensions,1-3

Component Weights,1-5

Electrical Requirements,1-6

Air, Vacuum, and System Fluid Requirements,1-6

Air Supply Requirements (NX-MC and NX-S8 with a Microplate

Shaking ALP only),1-6

Vacuum Supply Requirements,1-7

System Fluid Requirements (NXP-S8 only),1-8

CHAPTER 2: Preparing the Biomek NXP Instrument for Setup,2-1

Overview,2-1

Moving the NXP Instrument Crate to the Unpacking Location,2-1

Unpacking the NXP Instrument,2-2

Required Tools,2-2

Unpacking the Accessories,2-3

Unpacking the Instrument,2-5

Inspecting the NXP Instrument,2-6

Moving the NXP Instrument to the Installation Site,2-6

Placing the NXP Instrument on the Lab Bench,2-8

Contacting Your Field Service Engineer,2-8

CHAPTER 3: Preparing Cytomat Devices,3-1

Overview,3-1

Cytomat Device Specifications,3-2

Estimating Required Workspace Dimensions,3-3

Setting Up Optical Tables,3-3

xii

Contents

Unpacking an Optical Table,3-3

Setting Up a 1 m x 1 m Optical Table for the Cytomat 6001,3-4

Setting Up a .6 m x .9 m Optical Table for the Biomek NXP

Instrument and the Microplate Hotel,3-6

Optical Table Layout,3-8

Unpacking Cytomat Devices,3-11

CHAPTER 4: Preparing Other Integrated Devices,4-1

Overview,4-1

Dimensions for Integrated Devices,4-1

Electrical Component Requirements,4-3

Index

Beckman Coulter, Inc.

Warranty and Returned Goods Requirement

xiii

Illustrations

1.1 Recommendation for an Air Pressure Regulation System

Configuration,1-7

2.1 Fully Packaged NXP Instrument,2-3

2.2 Accessories Box Contents for the NXP Instrument Model

A31840,2-4

2.3 ‘U’ Brackets,2-5

3.1 Assembled 1 m x 1 m Optical Table,3-5

3.2 Assembled .6 m x .9 m Optical Table,3-7

3.3 Layout Showing .6 m x .9 m and 1 m x 1 m Optical Tables,3-9

3.4 Layout for .6 m x .9 m Optical Table,3-10

4.1 System Layout Dimension Changes,4-1

4.2 Dimensions for a Biomek NXP Instrument with Several

Integrated Devices,4-2

xiv

Tables

1.1 System Specifications,1-2

1.2 Dimensions Required,1-4

1.3 Biomek NXP Instrument Component Weights,1-5

1.4 Electrical Components and Requirements,1-6

2.1 Accessories by Model Number,2-4

3.1 Cytomat 2C Incubator Specifications,3-2

3.2 Cytomat 6001 HS Incubator Specifications,3-2

3.3 Cytomat Microplate Hotel Specifications,3-2

3.4 Cytomat ALP Electrical Requirements,3-3

4.1 Electrical Components and Requirements,4-3

B20063AC 1-1

CHAPTER 1

Preparing the Site

Preparation Overview

This preinstallation manual details the necessary site preparation required prior to the installation

of the Biomek NXP Laboratory Automation Workstation.

For preinstallation information for optional Cytomat incubators and storage units and other

optional integrated devices, Preparing Cytomat Devices.

Models

The information in this manual generally refers to both configurations of the Biomek NXP

instrument; if specific conditions apply to only one configuration, this manual identifies these

configurations as follows:

• NX-MC — Biomek NXP Multichannel Laboratory Automation Workstation

• NX-S8 — Biomek NXP Span-8 Laboratory Automation Workstation

Site Preparation

Pay careful attention to the specifications and requirements described in this manual. Accurate and

timely preparation allows the Beckman Coulter Field Service Engineer to install the Biomek NXP

instrument efficiently upon arrival. Appropriate site preparation includes making sure that:

• System specification requirements are met when the Biomek NXP instrument is installed (See

Biomek NXP System Specifications).

• Adequate work space is set up for the instrument and automation controller (see Work Area

Minimum Dimensions).

• The bench holding the Biomek NXP system supports the total installed weight of the

Biomek NXP instrument and any peripheral equipment (see Component Weights). The bench

must also be level and stable so that normal operations of the Biomek NXP instrument do not

cause the bench to shift, jerk, or sway.

• Electrical supply and power quality are adequate for operation (see Electrical Requirements).

• Sufficient air and vacuum are available for operating the entire system (see Air, Vacuum, and

System Fluid Requirements).

• Appropriate degassed system fluid is available for a Biomek NXP instrument equipped with a

Span-8 Pod (see System Fluid Requirements (NXP-S8 only)).

After you have prepared the site, unpacking the instrument and placing it on the workbench ready

for installation are your responsibilities.

B20063AC

1-2

Preparing the Site

Biomek NXP System Specifications

Table 1.1 presents system specifications and requirements for the Biomek NXP instrument.

Table 1.1 System Specifications

Item Description

Environment Indoor use only

Power Requirements 100–240 VAC, 50–60 Hz

Compressed Air Requirements

•NX-MC — Requires compressed air.

•NX-S8 — Only Span-8 instruments that

use a Microplate Shaking ALP require

compressed air.

Air Pressure: 60 - 100 psi of compressed air

414 - 690 kPa of compressed air

Air Flow: 2.25 cfm @ 60 psi

0.064 m3/min @ 414 kPa

System Fluid Requirements

•NX-S8 — Requires system fluid.

De-ionized or Distilled water

System fluid ambient operating temperature is

59°–86°F (15°–30°C).

System fluid should be degassed for 24 hours prior to use.

Dimensions base unit: •NX-MC — 36 in. (L) x 31 in. (W) x 34 in. (H); 91.44 cm (L)

x 78.74 cm (W) x 86.36 cm (H)

•NX-S8 — 36 in. (L) x 31 in. (W) x 44 in. (H); 91.44 cm (L)

x 78.74 cm (W) x 111.76 cm (H)

Weight:

Biomek NXP instrument (in packing crate)

Biomek NXP instrument

320 lbs. (145.2 kg)

190 lbs. (86.2 kg)

Ambient Operating Temperature 41°–86°F (5°–30°C)

Humidity Restrictions <85% (non-condensing) @ 86°F (30°C)

Altitude Restrictions up to 6562 ft (2000 m)

Installation Category Category II

Pollution Degree 2

Sound Pressure Level Maximum sound pressure: 82 dB

Maximum sound pressure at 1 meter away: 75 dB

Fuses US: 250 VAC, 3.15 amp, 5x20 mm, Slow-blow, UL recognized,

CSA certified

Europe: 250 VAC, 3.15 amp, 5x20 mm, Slow-blow, CENELEC

approved

Communications to Host RS-232 port

Communications to Tip Loader

•NX-MC — Uses a Tip Loader.

CAN

Communications to Active ALPs via the

Biomek NXP instrument

CAN

B20063AC 1-3

Preparing the Site

Work Area Minimum Dimensions 1

Work Area Minimum Dimensions

Use Table 1.2 to determine:

• Minimum dimensions required for the Biomek NXP instrument work area.

• Location for the automation controller and stand near the instrument bench.

NOTE The minimum bench length of 25 in. necessary to hold the Biomek NXP instrument is shorter than the

base of the instrument which is 36 in. If the bench is slightly shorter than the Biomek NXP instrument, be

sure to allow enough space on both sides for the instrument to overhang the bench.

Biomek Controller Windows 7: Biomek Software Version 4.1

The following specifications are the minimum requirements

needed.

Processor: Intel Core i5-2400 (3.1 GHZ) or better

Memory: 2 GB

Hard Drive: 250 GB or better

Optical Drive: DVD

Additional Software: Microsoft SQL Server 2005 Edition

Operating System: Windows 7, 64-bit with scripting enabled

Internet Browser: Internet Explorer 8

Windows 10: Biomek Software Version 4.2

The following specifications are the minimum requirements

needed:

CPU: Intel Core i5-8500 (3.0 GHz)

RAM: 8 GB

Hard Drive: 500 GB

Optical Drive: DVD

Monitor: 22", 1920 x 1800

Operating System: Windows 10, 64-bit

Table 1.1 System Specifications (Continued)

Item Description

B20063AC

1-4

Preparing the Site

Work Area Minimum Dimensions

Table 1.2 Dimensions Required

Component Minimum Dimensions Required

Biomek NXP instrument base unit •NX-MC — 36 in. (L) x 31 in. (W) x 34 in. (H); 91.44 cm (L)

x 78.74 cm (W) x 86.36 cm (H)

•NX-S8 — 36 in. (L) x 31 in. (W) x 44 in. (H); 91.44 cm (L)

x 78.74 cm (W) x 111.76 cm (H)

Minimum bench necessary to adequately

hold the Biomek NXP instrumenta

a. The dimensions for the lab bench in the above table do not include space for the automation controller or additional accessories. A lab bench

with shelving for accessories underneath the instrument is desirable.

25 in. (L) x 24 in. (W)

63.5 cm (L) x 61 cm (W)

CAUTION

The Biomek NXP instrument will overhang the edges of

a 25” x 24”(63.5 cm x 61 cm) bench. Make sure there

are no obstacles that will interfere with placement of

the instrument.

CAUTION

Make sure the bench can support the total installed

weight of the system. Refer to Table 1.3 to determine

the total weight of the system.

Rear access clearance 4 in. (10.2 cm)

Side access clearance 12 in. (30.5 cm)

B20063AC 1-5

Preparing the Site

Component Weights 1

Component Weights

Use Table 1.3 to determine the bench load requirements for the approximate installed weight of a

Biomek NXP instrument with ALPs.

Table 1.3 Biomek NXP Instrument Component Weights

Component Weight

Biomek NXP Instrument Approximately 190 lbs. (86.2 kg)

Tip Loader ALP 10 lbs. (4.5 kg)

1 x 1 Passive ALP 2 lbs. (.9 kg)

1 x 3 Passive ALP 4 lbs. (1.8 kg)

1 x 5 Passive ALP 6 lbs.(2.7 kg)

4 x 3 Passive ALP 15 lbs. (6.8 kg)

4 x 4 Passive ALP 24 lbs. (10.9 kg)

Stirring ALP 3 lbs. (1.3 kg)

Positive Position ALP 5 lbs. (2.3 kg)

Bar Code Reader ALP 4 lbs. (1.8 kg)

Microplate Shaking ALP 6 lbs. (2.7 kg)

Magnetic Bead ALP 5 lbs. (2.3 kg)

Orbital Shaker ALP 7 lbs. (3.2 kg)

B20063AC

1-6

Preparing the Site

Electrical Requirements

Make sure the proper electrical supply is available at the bench for the Biomek NXP instrument.

Table 1.4 defines the electrical requirements.

NOTE All AC devices are at 50/60 Hz.

Air, Vacuum, and System Fluid Requirements

Depending on configuration, the Biomek NXP instrument may require compressed air, a vacuum

supply, or system fluid.

Air Supply Requirements (NX-MC and NX-S8 with a Microplate Shaking ALP only)

Make sure the site has the following available at the lab bench:

• 60 – 100 psi of clean dry air (276 - 690 kPa)

NOTE An external filter/regulator may be required to meet air pressure requirements.

• Air flow of 2.25 cfm @ 60 psi (0.064 m3/min @ 276 kPa)

NOTE Make sure the lab site has a clean, dry air supply available at the lab bench.

• A 1/4 in. or 1/8 in. NPT female fitting to connect the air supply to the quick disconnect fitting

and 1/4” OD tubing supplied with the Biomek NXP instrument.

NOTE If house air is not available, or if house air will not consistently provide the recommended

pressure, an air compressor or air cylinder may be used to provide the required supply (see

Figure 1.1).

Table 1.4 Electrical Components and Requirements

Electrical Component Electrical Requirements

Base Unit 100–240 VAC @ 4 amps max.

Windows 7

CPU power requirements

Monitor

100–127 VAC @ 5 amps max.

200–240 VAC @ 3 amps max.

100–240 VAC @1.8 amps max

Windows 10

Automation Controller

Monitor

100-240VAC @ 2.5 amps

100-240VAC @ 1 amp

I/O Box 110–240 VAC @ 6.3 amps max

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Beckman Coulter Biomek NXP Preinstallation Manual

Beckman Coulter Biomek NXP Preinstallation Manual

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