Roche Cedex HiRes is a state-of-the-art analyzer designed to provide fast and accurate results for your research or clinical needs. With its advanced capabilities, it offers a wide range of applications, including cell counting, cell viability assessment, and cell size determination. The Cedex HiRes excels in both precision and throughput, delivering reliable data to support your critical decisions.
Roche Cedex HiRes is a state-of-the-art analyzer designed to provide fast and accurate results for your research or clinical needs. With its advanced capabilities, it offers a wide range of applications, including cell counting, cell viability assessment, and cell size determination. The Cedex HiRes excels in both precision and throughput, delivering reliable data to support your critical decisions.
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For use in quality control/manufacturing process only.
Preparing and Maintaining the Analyzer — (November 2019)
Moving parts of the Multi Sampler may cause hand injuries. The Multi Sampler needle
may cause injuries during operation. Never use the Cedex HiRes Analyzer without the
protective cover in place for the Multi Sampler.
Changing the Reagent Kit
To install or change the Reagent Kit:
1
If the Liquid Management system has been primed, click on the HWM button in Cedex
Control
Center to open the Hardware Management dialog box.
2
Place a sample cup in the DefaultCup position on the Multi Sample Tray, and click on
LM SHUTDOWN in the Hardware Management dialog box to shut down the Liquid
Management.
3
Open the reagent chamber in the Cedex HiRes Analyzer by pushing the front upwards
until it
clicks into place.
4
Remove the old Reagent Kit from the tray and dispose of the old reagent containers.
5
Open the new Reagent Kit and remove the lids from the individual containers.
6
Place the new Reagent Kit containers in the appropriate positions in the Reagent Tray.
The positions for the reagents are marked on the Reagent Tray.
7
Close the front cover by pulling it all the way down. When the front cover is closed, the
capillaries are automatically correctly positioned in the individual containers.
8
Select the Reagent Kit Status option in the Functions menu of the Cedex Control Center
to open the Reagent Kit Status dialog box.
9
Click on the REPLACE ALL CONTAINERS button in the right-hand corner of the Reagent Kit
Status
dialog box to confirm the changing of the Reagent Kit. The Reagent Control display at
the bottom
right-hand corner of the Cedex Control Center will turn from red to green and
indicate the number of runs left.
10
Place a sample cup in the DefaultCup position
on the Multi Sample Tray, and perform a
Prime via the Hardware Management dialog box
(HWM button on the Cedex Control
Center).
■
Refilling Individual Containers
Reagents can be refilled, or in the case of waste, emptied individually.
1
Shut down the liquid management via the Hardware Management dialog box as in Steps
1 to 2 of “Changing the Reagent Kit”.
2
Open the reagent chamber and remove the Reagent Tray as described in Step 3 of
“Changing the Reagent Kit ”.
3
Remove the empty reagent bottles and place fresh reagent refill containers in the positions
indicated on the Reagent Tray. Empty waste container, if necessary.
4
Place the Reagent Tray back in position and close the reagent chamber.
5
Select the Reagent Kit Status option in the Functions menu of the Cedex Control Center
to open the Reagent Kit Status dialog box.
6
Confirm the refilling of each reagent container individually by clicking on the respective SET
FULL button (or EMPTY button for waste) in the Reagent Kit Status dialog box.
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Cedex HiRes Software 2.5 Quick Guide
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112019
For use in quality control/manufacturing process only.
CEDEX is a trademark of Roche.
All other product names and trademarks are the property of their respective owners.
Preparing and Maintaining the Analyzer — (November 2019)
Prescan Failure
If the software determines that there are impurities in the flow chamber, a message, “Dirt
or bubbles detected during prescan!” will appear. When the measurement is viewed in the
Measurement dialog box, there will be no check in the Valid checkbox below the Image area.
Do the following:
1
Click on the VIEW PRESCAN button in the Measurement dialog box, a part of the prescan
image
will appear in the Image dialog box.
2
Double-click on the partial prescan image to open the complete image in an Image View
dialog box
.
3
If the flow chamber appears to have had dirt or impurities in it, clean the system with
Standard Clean or Chamber Clean 2 before performing a new measurement. To perform
a cleaning routine, click on the CLEAN button in the Cedex Control Center to open the
Cleaning dialog box. Click on Standard Clean and/or Chamber Clean 2.
4
If the prescan fails again after performing cleaning routines, contact your local Roche
Service representative.
■
The Cedex Sample Cup from the last measurement should remain placed in the DefaultCup
position on the Multi Sample Tray during the complete cleaning procedure. It should only be
removed when a new Cedex Sample Cup has been placed in position for the next measure-
ment.
Interrupting a Measurement
An orange EMERGENCY STOP button is located on the left-hand side of the Measurement
dialog box and can be activated during the measuring procedure to interrupt the analysis
process. If the EMERGENCY STOP is selected, a message will appear asking, “Do you want to
cancel the process?”.
c Click on YES to stop the system immediately. If YES is selected, the EMERGENCY STOP
button will change to read Unlock Queue. The system must be unlocked by clicking on
this button before more measurements can be run.
c Click on NO to put the process on hold until another action is chosen. If NO is selected,
the EMERGENCY STOP button will change to read Resume. Click on this button to
resume the measurement process.
Use the EMERGENGY STOP button only when necessary as measurement data may be
lost.
Cedex HiRes Software 2.5 Quick Guide
Roche Diagnostics GmbH
Sandhofer Straße 116
68305 Mannheim
Germany
© 2019 Roche Diagnostics.
All rights reserved.
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Roche Cedex HiRes is a state-of-the-art analyzer designed to provide fast and accurate results for your research or clinical needs. With its advanced capabilities, it offers a wide range of applications, including cell counting, cell viability assessment, and cell size determination. The Cedex HiRes excels in both precision and throughput, delivering reliable data to support your critical decisions.
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