Thermo Fisher Scientific Vanquish Neo Binary Pump Owner's manual

thermoscientific

Vanquish

Neo Binary Pump

VN-P10

Operating Manual

4822.5101-EN Revision 1.0 •July 2023

*4822.5101-EN-1.0*

Original Operating Manual

The hardware descriptions in this manual revision refer to devices: VN-P10-A.

Trademarks

Acrobat, Adobe, and Adobe Reader are trademarks of Adobe Systems Incorporated.

Microsoft and Windows are trademarks of Microsoft Corporation.

MP35N is a trademark of SPS Technologies.

PharMed is a trademark of Saint-Gobain Performance Plastics.

Torx is a trademark of Acument Intellectual Properties, LLC.

All other trademarks are property of Thermo Fisher Scientific and its subsidiaries.

Disclaimer

Thermo Fisher Scientific Inc. provides this document to its customers with a product purchase to

use in the product operation. The document is copyright protected; any reproduction of the

whole or any part of this document is strictly prohibited, except with the written authorization

of Thermo Fisher Scientific Inc.

This manual is provided "as is." The contents of this manual are subject to being changed,

without notice, in future revisions.

Thermo Fisher Scientific Inc. makes no representations that this document is complete,

accurate, or error-free. Thermo Fisher Scientific Inc. assumes no responsibility and will not be

liable for any errors, omissions, damage, or loss that might result from any use of this document,

even if the information in the document is followed properly.

This document is not part of any sales contract between Thermo Fisher Scientific Inc. and a

purchaser. This document shall in no way govern or modify any Terms and Conditions of Sale.

The Terms and Conditions of Sale shall govern all conflicting information between the two

documents.

Printed manual version only

Printed in Germany on 100% chlorine-free bleached, high-white paper that is produced in an

environmentally friendly process, leading to a paper profile of zero CO2 emissions.

Manufacturer's address

Dionex Softron GmbH, Part of Thermo Fisher Scientific, Dornierstrasse 4, D-82110 Germering

Contacting Us

You can find information on all of the different support services of

Thermo Fisher Scientific by navigating the following website:

https://www.thermofisher.com/us/en/home/technical-resources/

contact-us.html

Contacting Us

Neo Binary Pump (VN-P10)

Operating Manual

Page 3

Contacting Us

Page 4 Neo Binary Pump (VN-P10)

Operating Manual

Contents

Neo Binary Pump (VN-P10)

Operating Manual

Page 5

Contents

1 Using this Manual....................................................................... 11

1.1 About this Manual ............................................................................................... 12

1.2 Conventions for Safety Messages ........................................................................ 13

1.3 Special Notices ..................................................................................................... 14

1.4 Typographical Conventions.................................................................................. 15

1.5 Reference Documentation................................................................................... 16

2 Safety......................................................................................... 17

2.1 Safety Symbols and Signal Words ........................................................................ 18

2.1.1 Safety Symbols and Signal Words in this Manual..................................... 18

2.1.2 Observing this Manual ............................................................................. 18

2.1.3 Safety Symbols on the System ................................................................. 19

2.1.4 Rating Plate .............................................................................................. 19

2.2 Intended Use........................................................................................................ 20

2.3 Safety Precautions ............................................................................................... 21

2.3.1 General Safety Information...................................................................... 21

2.3.2 Qualification of the Personnel ................................................................. 22

2.3.3 Personal Protective Equipment................................................................ 22

2.3.4 Electrical Safety Precautions .................................................................... 23

2.3.5 General Residual Hazards......................................................................... 24

2.3.6 In Case of Emergency ............................................................................... 25

2.4 Compliance Information ...................................................................................... 26

3 Overview.................................................................................... 27

3.1 Features ............................................................................................................... 28

3.2 Components......................................................................................................... 29

3.3 Pump Interior Components ................................................................................. 30

3.4 Pump Operating Principle .................................................................................... 31

3.5 Purging (Overview) .............................................................................................. 33

3.6 Leak Detection ..................................................................................................... 35

3.7 Piston Seal Wash System ..................................................................................... 36

3.8 Solvent Rack......................................................................................................... 37

Contents

Page 6 Neo Binary Pump (VN-P10)

Operating Manual

3.9 System Base ......................................................................................................... 38

3.9.1 System Base Parts .................................................................................... 38

3.9.2 System Base Lock ..................................................................................... 39

3.10 Power On/Off Control.......................................................................................... 40

3.11 Operation............................................................................................................. 42

4 Unpacking .................................................................................. 43

4.1 Damaged Packaging, Defective on Arrival ........................................................... 44

4.2 Scope of Delivery ................................................................................................. 45

4.3 Unpacking the System Base and Solvent Rack..................................................... 46

4.4 Unpacking the Pump............................................................................................ 47

5 Installation ................................................................................. 49

5.1 Safety Guidelines for Installation......................................................................... 50

5.2 Installation Flow Chart ......................................................................................... 51

5.3 Site Requirements................................................................................................ 52

5.3.1 Workbench............................................................................................... 52

5.3.2 Power Considerations .............................................................................. 53

5.3.3 Power Cord............................................................................................... 54

5.3.4 Condensation ........................................................................................... 54

5.3.5 Operating Conditions ............................................................................... 55

5.4 Setting Up the Hardware ..................................................................................... 56

5.4.1 System Stack Setup .................................................................................. 56

5.4.2 Connecting Cables .................................................................................... 60

5.4.3 Moving the System Stack (Unlocking/Locking) ........................................ 65

5.5 Accessing the Interior Components..................................................................... 68

5.6 Setting Up the Flow Connections......................................................................... 69

5.6.1 Guiding Capillaries and Tubing Through the System................................ 69

5.6.2 Connecting Fittings, Capillaries, and Tubing ............................................ 70

5.6.3 Connecting the Waste Lines..................................................................... 72

5.6.4 Connecting the Solvent Lines ................................................................... 75

5.6.5 Installing the Seal Wash System............................................................... 78

5.6.6 Filling the Seal Wash Reservoir ................................................................ 80

5.6.7 Installing the Viper Guard Connector on the Flowmeter Outlet.............. 82

5.7 Turning On the System......................................................................................... 83

5.8 Preparing the Pump for Initial Operation ............................................................ 85

Contents

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Operating Manual

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6 Operation................................................................................... 87

6.1 Safety Guidelines for Operation........................................................................... 88

6.2 Solvent and Additive Information........................................................................ 89

6.2.1 General Compatibility .............................................................................. 89

6.2.2 Allowed pH Ranges................................................................................... 89

6.2.3 Allowed Concentrations ........................................................................... 89

6.2.4 Use of Solvents and Additives .................................................................. 90

6.3 Control Elements ................................................................................................. 92

6.3.1 Keypad...................................................................................................... 92

6.3.2 Status Indicators....................................................................................... 94

6.4 Power On/Off Control.......................................................................................... 96

6.5 Preparing the Pump for Operation ...................................................................... 97

6.6 Optimizing the Performance................................................................................ 98

6.6.1 Dependency of Available Pump Pressure and Flow Rate......................... 98

6.6.2 Adding Custom Solvents to the Calibration Table.................................... 99

6.6.3 Adjusting the Pump Flow Sensor Offsets ............................................... 101

6.7 Shutting Down the System................................................................................. 103

6.7.1 Short-Term Shutdown............................................................................ 103

6.7.2 Long-Term Shutdown............................................................................. 103

6.7.3 Restart after Long-Term Shutdown........................................................ 105

7 Maintenance and Service ......................................................... 107

7.1 Introduction to Maintenance and Service ......................................................... 108

7.2 Safety Guidelines for Maintenance and Service ................................................ 109

7.3 General Rules for Maintenance and Service...................................................... 111

7.4 Routine and Preventive Maintenance ............................................................... 112

7.4.1 Maintenance Plan .................................................................................. 112

7.4.2 Flushing the Pump to Avoid Contamination .......................................... 114

7.4.3 Flushing the Pump with Persistent Contamination Only ....................... 114

7.4.4 Cleaning or Decontaminating the Device............................................... 116

7.5 Pump Head Maintenance .................................................................................. 118

7.5.1 Overview of Pump Head Parts ............................................................... 119

7.5.2 Replacing the Pump Head ...................................................................... 120

7.5.3 Replacing the Pistons ............................................................................. 124

7.5.4 Cleaning the Piston................................................................................. 126

7.5.5 Replacing the Support Ring .................................................................... 127

7.5.6 Replacing the Piston Seal ....................................................................... 132

Contents

Page 8 Neo Binary Pump (VN-P10)

Operating Manual

7.5.7 Replacing the Seal Wash Seal................................................................. 139

7.5.8 Replacing the Pump Head Seals ............................................................. 143

7.5.9 Maintaining the Pump Head Check Valves............................................. 148

7.6 Flowmeter Maintenance.................................................................................... 154

7.6.1 Replacing the Flowmeter Filter .............................................................. 154

7.6.2 Replacing the Flowmeter Waste Line..................................................... 156

7.6.3 Replacing the Viper Guard Connector on the Flowmeter Outlet........... 158

7.7 Solvent Line Maintenance.................................................................................. 159

7.7.1 Emptying the Solvent Lines .................................................................... 159

7.7.2 Replacing Solvent Lines from Reservoir to Pump................................... 160

7.7.3 Replacing Solvent Lines from Shut-off Valve to Pump Head.................. 164

7.7.4 Replacing the Solvent Line Filter ............................................................ 165

7.8 Seal Wash System Maintenance ........................................................................ 167

7.8.1 Testing the Seal Wash System for Leakage ............................................ 167

7.8.2 Replacing the Seal Wash Reservoir Line................................................. 168

7.8.3 Replacing the Peristaltic Tubing in the Seal Wash Pump ....................... 171

7.8.4 Replacing the Seal Wash Lines between Seal Wash Pump and Seal Wash

Detector ................................................................................................. 173

7.8.5 Replacing the Seal Wash Detector ......................................................... 174

7.9 Solvent Rack Replacement................................................................................. 177

7.10 Bottle Insert Replacement ................................................................................. 179

7.10.1 Removing the Bottle Insert .................................................................... 179

7.10.2 Installing the Bottle Insert...................................................................... 180

7.11 Main Power Fuse and Door Replacement ......................................................... 181

7.11.1 Replacing the Main Power Fuses ........................................................... 181

7.11.2 Replacing the Doors ............................................................................... 182

7.12 Extending the System Stack by Another Module............................................... 184

7.13 Transporting or Shipping the System................................................................. 186

7.13.1 Preparing the Device for Transport........................................................ 186

7.13.2 Dismounting the System Stack............................................................... 187

7.13.3 Shipping the Pump or System ................................................................ 189

7.14 Replacing the Slide-In Module ........................................................................... 190

7.14.1 Removing the Pump Slide-In Module..................................................... 190

7.14.2 Returning the Slide-In Module ............................................................... 191

7.14.3 Installing the Slide-In Module ................................................................ 192

7.14.4 Setting Up the Slide-In Module .............................................................. 194

Contents

Neo Binary Pump (VN-P10)

Operating Manual

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8 Troubleshooting ....................................................................... 195

8.1 General Information about Troubleshooting..................................................... 196

8.2 Messages............................................................................................................ 197

8.2.1 Common Messages ................................................................................ 197

8.2.2 Pump Messages ..................................................................................... 201

8.3 Testing for Liquid Leaks...................................................................................... 208

9 Specifications ........................................................................... 211

9.1 Pump Performance Specification....................................................................... 212

9.2 System Base and System Controller................................................................... 214

9.3 Physical Specifications ....................................................................................... 215

9.3.1 Environmental Specifications ................................................................. 215

9.3.2 Power Requirements.............................................................................. 215

9.3.3 Dimensions............................................................................................. 215

9.3.4 Emission Sound Pressure Level .............................................................. 216

9.3.5 Weight.................................................................................................... 216

10 Accessories, Consumables and Replacement Parts ................... 217

10.1 General Information .......................................................................................... 218

10.2 Ship Kit ............................................................................................................... 219

10.3 Optional Accessories.......................................................................................... 221

10.4 Consumables and Replacement Parts................................................................ 222

10.4.1 Capillary Accessories and Drainage........................................................ 222

10.4.2 System Replacement Parts and Tools .................................................... 222

10.4.3 Solvents and Wash Systems ................................................................... 223

10.4.4 Pump Replacement Parts ....................................................................... 224

10.4.5 Interface Cables and Power Cords ......................................................... 226

11 Appendix.................................................................................. 227

11.1 Compliance Information .................................................................................... 228

11.1.1 Declarations of Conformity .................................................................... 228

11.1.2 WEEE Compliance .................................................................................. 229

11.1.3 FCC Compliance...................................................................................... 229

11.1.4 Manual Release History.......................................................................... 230

11.2 Digital I/O ........................................................................................................... 231

Index ........................................................................................ 233

Contents

Page 10 Neo Binary Pump (VN-P10)

Operating Manual

1 • Using this Manual

Neo Binary Pump (VN-P10)

Operating Manual

Page 11

1 Using this Manual

This chapter provides information about this manual, the conventions

used throughout the manual, and the reference documentation that is

available in addition to this manual.

1 • Using this Manual

Page 12 Neo Binary Pump (VN-P10)

Operating Manual

1.1 About this Manual

This manual describes the functional features and operating principle of

your Vanquish™ device and provides instructions for installation, set up,

start up, shut down, operation, maintenance and troubleshooting.

This manual also contains safety messages, precautionary statements,

and special notices. Follow these properly to prevent personal injury,

damage to the device, or loss of data.

The pump is also referred to as module or device in this manual. The

term system refers to configuration with pump, system base, solvent

rack, and Vanquish User Interface.

Notes on Illustrations

•Illustrations in this manual are provided for basic understanding.

They may vary from the actual model of the system or component.

•No claims can be derived from the illustrations in this manual.

1 • Using this Manual

Neo Binary Pump (VN-P10)

Operating Manual

Page 13

1.2 Conventions for Safety Messages

The safety messages and precautionary statements in this manual

appear as follows:

•Safety messages or precautionary statements that apply to the

entire manual and all procedures in this manual are grouped in the

Safety chapter.

•Safety messages or precautionary statements that apply to an entire

section or to multiple procedures in a section appear at the

beginning of the section to which they apply.

•Safety messages that apply to only a particular section or procedure

appear in the section or procedure to which they apply. They appear

different from the main flow of text.

Safety messages are often preceded by an alert symbol and/or alert

word. The alert word appears in uppercase letters and in bold type.

Make sure that you understand and follow all safety messages

presented in this manual.

1 • Using this Manual

Page 14 Neo Binary Pump (VN-P10)

Operating Manual

1.3 Special Notices

Special notices and informational notes in this manual appear different

from the main flow of text. They appear in boxes and a note label

identifies them. The label text appears in uppercase letters and in bold

type.

NOTICE

Highlights information necessary to prevent damage to the device or

invalid test results.

TIP Highlights information of general interest or helpful information that

can make a task easier or optimize the performance of the device.

1 • Using this Manual

Neo Binary Pump (VN-P10)

Operating Manual

Page 15

1.4 Typographical Conventions

These typographical conventions apply to the descriptions in this

manual:

Data Input and Output

The following appears in bold type:

•Input that you enter by the keyboard or that you select with the

mouse

•Buttons that you click on the screen

•Commands that you enter by the keyboard

•Names of, for example, dialog boxes, properties, and parameters

For brevity, long expressions and paths appear in the condensed form,

for example: Click File > Save as.

References and Messages

•References to additional documentation appear italicized.

•Messages that appear on the screen are identified by quotation

marks.

Viewpoint

If not otherwise stated, the expressions left and right in this manual

always refer to the viewpoint of a person that is facing the device from

the front.

Particularly Important Words

Particularly important words in the main flow of text appear italicized.

Electronic Manual Version (PDF)

The electronic version (PDF) of the manual contains numerous links that

you can click to go to other locations within the manual. These include:

•Table of contents entries

•Index entries

•Cross-references (in blue text)

1 • Using this Manual

Page 16 Neo Binary Pump (VN-P10)

Operating Manual

1.5 Reference Documentation

In addition to this manual, other documentation is available.

Thermo Fisher Scientific provides up-to-date operating manuals as PDF

(Portable Document Format) files that you can access from our customer

manuals web site. To open and read the PDF files, Adobe™ Reader™ or

Adobe™ Acrobat™ is required.

Go to the following web site: www.thermofisher.com/HPLCmanuals

Hardware Documentation

For information on how to install, start up, maintain and troubleshoot

the Vanquish User Interface, refer to the Vanquish User Interface

Installation Guide.

Third-Party Documentation

Refer also to the user documentation provided by the manufacturers of

third-party components and materials, for example, Safety Data Sheets

(SDSs).

2 • Safety

Neo Binary Pump (VN-P10)

Operating Manual

Page 17

2 Safety

This chapter provides general and specific safety information and

informs about the intended use of the device.

2 • Safety

Page 18 Neo Binary Pump (VN-P10)

Operating Manual

2.1 Safety Symbols and Signal Words

2.1.1 Safety Symbols and Signal Words in this Manual

This manual contains safety messages to prevent injury of the persons

using the device.

The safety symbols and signal words in this manual include the

following:

Always be aware of the safety information. Do not proceed until you

have fully understood the information and consider the consequences of

what you are doing.

CAUTION

Indicates a hazardous situation that, if not avoided, could result in minor

or moderate injury.

WARNING

Indicates a hazardous situation that, if not avoided, could result in

serious injury.

2.1.2 Observing this Manual

Observe the following:

•Before installing or operating the device, read this manual carefully

to be familiar with the device and this manual. The manual contains

important information with regard to user safety as well as use and

care of the device.

•Always keep the manual near the device for quick reference.

•Save this manual and pass it on to any subsequent user.

Read, understand, and comply with all safety messages and

precautionary statements presented in this manual.

2 • Safety

Neo Binary Pump (VN-P10)

Operating Manual

Page 19

2.1.3 Safety Symbols on the System

The table lists the safety symbols that appear on the system base, pump,

and solvent rack or on labels affixed to the system. Follow the safety

notices in this manual to prevent the risk of operator injury or damage

to the system.

Symbol Description

Indicates a potential hazard. Refer to this manual to avoid the risk of

personal injury and/or to prevent damage to the device.

—

Ο

Power supply is on

Power supply is off

Indicates a power button that switches the system between on and

off states.

Indicates a power button that switches the system controller on and

off.

Indicates alternating current.

Indicates a terminal for protective grounding

Can be used to attach a device for protective grounding, for example,

a column.

2.1.4 Rating Plate

The rating plate is present on the device near the electrical connections.

The rating plate indicates the serial number, part number, module

name, revision number (if any), and the line and fuse rating.

TIP An additional type label on the leak tray of the device indicates the

module name, serial number, part number, and revision number (if any).

To facilitate device identification, have the information from this label

available when communicating with Thermo Fisher Scientific.

2 • Safety

Page 20 Neo Binary Pump (VN-P10)

Operating Manual

2.2 Intended Use

The device is intended to be part of the Vanquish system.

The intended use of the Vanquish system is to analyze mixtures of

compounds in sample solutions.

The device is for use by qualified personnel and in laboratory

environment only.

The device and Vanquish system are intended to be used as General

Laboratory Equipment (GLE).

They are not intended for use in diagnostic procedures.

Laboratory Practice

Thermo Fisher Scientific recommends that the laboratory in which the

Vanquish system is used follow best practices for LC analyses. This

includes among others:

•Using appropriate standards

•Regularly running calibration

•Establishing shelf life limits and following them for all consumables

used with the system

•Running the system according to the laboratory's verified and

validated 'lab developed test' protocol

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Thermo Fisher Scientific Vanquish Neo Binary Pump Owner's manual

Thermo Fisher Scientific Vanquish Neo Binary Pump Owner's manual

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