Roche cobas c 311 Short Guide

Brand: Roche

Model: cobas c 311

Type: Short Guide

Roche cobas c 311 is a compact, fully automated clinical chemistry analyzer that offers a wide range of testing capabilities for small to medium-sized laboratories. With its user-friendly interface, reliable performance, and comprehensive testing menu, the cobas c 311 streamlines laboratory workflow and delivers accurate results quickly and efficiently.

cobas c 311 analyzer Short Guide

Preparing the analyzer ............................................................................................... 2

Starting the analyzer................................................................................................... 2

System Overview – Workflow Guide ......................................................................... 2

Daily Maintenance................................................................................................. 2

Sample Data Clear ................................................................................................ 2

Reagent Preparing ................................................................................................ 3

Calibration and QC Select.................................................................................... 4

End of routine........................................................................................................ 4

Application, Calibration and QC set up .................................................................... 5

Loading application parameters from cobas link .............................................. 5

Checking parameter settings for each test ........................................................ 5

Assigning tests to the photometric or ISE unit .................................................. 5

Assigning tests to test keys................................................................................. 6

Loading calibrator data from cobas link............................................................. 6

Adding calibrator data manually ......................................................................... 6

Loading control data from cobas link ................................................................. 7

Adding control data manually.............................................................................. 7

Checking the Report Format................................................................................ 8

Assigning sample positions for non-barcoded calibrators............................... 8

Assigning sample positions for non-barcoded controls................................... 8

Customer Maintenance Overview ............................................................................. 9

cobas c 311 analyzer Short Guide

Preparing the analyzer

Always take suitable safety measures as described in the Operator’s Manual.

1 Check that the container for highly concentrated waste is clean and empty.

2 Check for any leaks inside or around the instrument.

3 Check that the cell covers, pipetter probes, ISE sipper nozzle, and the rinse nozzles are clean.

If a trouble occurs, take the necessary remedial action.

Starting the analyzer

1 Switch on instrument. When the automatic power up is specified in the analyzer software, the pipe

function will be executed automatically.

2 Switch on control unit computer.

3 Switch on water supply.

4 Logon to the analyzer software using your operator ID and password.

Note: When the analyzer is in sleep mode, it starts up automatically by using the sleep pipe function

(Power Up Pipe with starting time).

System Overview – Workflow Guide

Daily Maintenance

1 Check for alarms.

2 Perform required maintenance action or maintenance pipe function:

Daily

Maintenance

Select

Execute

Sample Data Clear

All measurement results of routine and STAT samples will be deleted. The measurement results of

quality control samples will be moved to the QC view area of data storage control section.

Sample

Data Clear

Clear or Backup and Clear

cobas c 311 analyzer Short Guide

Reagent Preparing

1 Select the Preventive Action check box on the System Overview screen.

Reagent

Preparing

Reagent Load/

Unload List

Yes

The Reagent Load list will be printed for reagents with yellow, purple, or red alarm.

3 Load reagents onto the instrument according to the reagent load list.

4 Remove all empty cobas c packs from the analyzer.

Replacing ISE reagents

1 Before replacing a reagent bottle, put the analyzer in Maintenance mode or Shutdown status.

2 After replacement turn the maintenance switch back to Operation mode (or power up the analyzer if

it was in Shutdown status).

3 Perform a Reagent Prime if an ISE Ref. or ISE IS bottle has been replaced:

Reagent

Preparing

Reagent Prime

4 Select all.

Execute

6 Recalibrate the ISE unit before you resume routine operation.

Module System Reagent Bottle size Notes

NaOH-D 2.0 L CellCln Position 1

Acid Wash Solution 2.0 L CellCln Position 2

Multiclean 70 mL SmpCln Position 1

SMS 70 mL SmpCln Position 2

Reagent

Volume Reset

NaCl 9% Diluent c pack DIL on reagent disk

NaOH-D c pack D1 on reagent disk

SMS c pack D2 on reagent disk

Photometric

unit

Hitergent c pack Hit-D on reagent disk

ISE Ref. 300 ml

ISE Dil. 300 ml

ISE unit

ISE IS 600 ml

Reagent

Level Reset

cobas c 311 analyzer Short Guide

Calibration and QC Select

The analyzer automatically recommends calibrations and controls to be performed. But the

recommended calibrations and QCs must be confirmed by the operator before they can be

measured.

Calibration and

QC Select

Recommended

2 Print the Calibrator and QC Load List:

3 Load calibrator and QC samples onto the analyzer according to the calibrator and QC load list.

Start

End of routine

1 Load wash solutions for ISE wash:

Pos. W1: ISE Cleaning Solution SysClean

Pos. W2: ISE Activator

SmpCln Position 1: Multiclean

Utility

Maintenance

3 Select maintenance item (10) ISE Wash.

Select

Execute

cobas c 311 analyzer Short Guide

Application, Calibration and QC set up

Loading application parameters from cobas link

Utility

Application

Download

2 Select one of the available search conditions.

4 Select the check box of the parameters to be downloaded.

Download

6 Check that the parameters have been downloaded.

Note: For the first installation the parameters for diluent and cleaners have to be downloaded.

Checking parameter settings for each test

Utility

Application

Analyze

Utility

Application

Calib.

3 Change to QC Violation, if required.

Utility

Application

Range

5 If required, change the Unit, define a Report Name, select Automatic Rerun, define Repeat Limit,

Control Interval Time, AutoQC On Board Stability time, Qualitative fields and Expected Values.

Utility

Application

Others

7 Enter the Calibrator Code for ISE tests.

Assigning tests to the photometric or ISE unit

Utility

Module Set

Test

Assignment

2 Check if the Assign check box is active for each test.

3 Select Mandatory, if a reagent has to be on board all the time.

4 Select Na, K, Cl or Na, K (ISE).

cobas c 311 analyzer Short Guide

Assigning tests to test keys

Utility

System

Key Setting

2 Select an empty test key.

3 Select a test.

Update

Loading calibrator data from cobas link

Calibration

Install

Download

2 Select one of the available search conditions.

4 Select the check box of the calibrators to be downloaded.

Download

6 Check that the calibrator data has been downloaded.

Adding calibrator data manually

Calibration

Install

2 Select a blank line.

Add

3 Type all necessary data in the Add Calibrator window.

The new calibrator appears on the calibrator list.

Edit

5 Type in the concentration values for each test.

Update

cobas c 311 analyzer Short Guide

Loading control data from cobas link

Install

Download

2 Select one of the available search conditions.

4 Select the check box of the control to be downloaded.

Download

6 Check that the control data has been downloaded.

Adding control data manually

Install

2 Select a blank line.

Add

3 Type all necessary data in the Add Control window.

The new control appears on the control list.

Edit

5 Enter Target mean, Target SD, and confidence limits High and Low, if necessary.

Update

Activating control tests:

Install

2 Select a control from the list on the left.

3 Select a test to be activated from the list on the right.

Activate Test

Activated test are highlighted green.

cobas c 311 analyzer Short Guide

Checking the Report Format

Utility

Report Format

Area: Print Order

2 Check if a Line number is defined for each test. Otherwise this result will not be printed.

Assigning sample positions for non-barcoded calibrators

Calibration

Calibrator

Position

Assignment

2 Select the calibrator to be assigned from the list on the left.

3 Select an empty sample position from the list on the right.

Assign-->

5 To undo an assignment

<--Remove

6 After all assignments are completed:

Assigning sample positions for non-barcoded controls

Control

Position

Assignment

2 Select the control to be assigned from the list on the left.

3 Select the corresponding sample position from the list on the right.

Add-->

5 To undo the assignment

<--Remove

6 After all assignments are completed:

cobas c 311 analyzer Short Guide

Customer Maintenance Overview

Always take suitable safety measures as described in the Operator’s Manual.

Daily Every 2 months

Clean pipetter probes and ISE sipper

[M2]

Every 2 months or 9000 tests: Replace

ISE measuring cartridges [M14]

Clean cell rinse nozzles [M3]

Clean the ISE drain port [M4]

Quarterly

Empty the waste solution container Clean the ultrasonic mixer [M15]

3,2

Check the drain tube of the vacuum

tank (empty it if necessary)

Replace the ISE pinch valve tubing

[M16]

Clean up instrument surfaces

Replace the ISE sipper tubing [M17]

Daily Sleep pipe

Every 3 months or 112,500 tests (56,250

tests for ISE): Replace the syringe seals

[M18]

Perform (10) ISE wash [M1]

(W1: SysClean, W2: Activator)

Every 6 months

Only if running DAT assays:

Perform (10) ISE Wash and (6) Wash

Reaction Parts

Clean the inlet water filter [M19]

Vacuum clean the cooling fan [M20]

Every 750 hours or if photometer check

value exceeds 14,000:

Replace the photometer lamp [M21]

Weekly

Replace the ISE ref. cartridge [M22]

Perform (6) Wash Reaction Parts and

(3) Cell blank [M5]

Clean cell covers [M6]

Clean the probe rinse stations

3,2

and

drying cylinders

[M7]

As needed

Check / clean the water tank [M8]

Eliminate clogging of sample / reagent

probe (sample probe: 0.2 mm, reagent

probe 0.5 mm stainless steel wire) or

replace probes [M23]

Monthly

Replace cell rinse nozzle tips [M24]

Replace reaction cells and clean

incubator bath [M9]

2 or 3

Drain the vacuum tank [M25]

Clean ISE Ref. aspiration filter [M10]

4,2

Clean detergent aspiration filters

[M11]

4,2

Vacuum clean the radiator filter [M12]

Perform (12) Flow path wash

(Cell wash II) [M13]

with 70% Ethanol

with deionized water

with 2% Hitergent solution

with tap water

Roche cobas c 311 Short Guide

Roche cobas c 311 Short Guide

Roche cobas c 311 Short Guide

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