Corning Ascent® FBR PD System Peristaltic Pump Owner's manual

Brand: Corning

Model: Ascent® FBR PD System Peristaltic Pump

Type: Owner's manual

Corning® Ascent® FBR PD System

Peristaltic Pump

Guidelines for Use

The Corning Ascent Fixed Bed Reactor (FBR) PD System consumables (Cat. Nos. 6971 - 6976) use high quality tubing designed for

extended-use operations with peristaltic pumps for the recirculation pump section. As with all peristaltic pumps, in rare cases of

prolonged use or improper loading, tubing can wear abnormally, fracture, and eventually leak. The following are best practices to load and

monitor tubing to prevent leaks from occurring on the Ascent FBR PD System.

◗During initial loading of the tubing loop through the recirculation pump or when opening the pump head for tubing inspection, tubing

should be taut and centered in the pump channel prior to closing the pump head. A slight tension can be placed on the tubing by

manually sliding the consumable sensor tray away from the pump head while closing the pump head (Figure 1). The tray may retract

slightly following release.

◗Following the Media Maintenance Phase, the tubing should be inspected for proper centering in the channel and re-tensioned, as the

tubing may stretch slightly during initial use (Figures 2 and 3).

◗Discoloration and attening are normal during peristaltic pumping operation (Figure 4), and external particulate generation on the

tubing and pump head during pumping is common. Particulate should be removed from the pump head regularly as it is observed.

Particulates can be removed using a lint-free wipe. Excessive particulate generation can be a sign of abnormal or excessive tubing wear.

Additional inspection, centering and tensioning may be recommended in these cases.

◗For operations with consistent high RPM (>250) and extended time periods (>3 days), the tubing should be inspected daily for abnormal

wear per the pump and tubing manufacturers’ recommendations and repositioned in the center of the rollers. If the presence of deep

ssures, gouges, or cuts through the thickness of tubing are observed, the risk of the tube leaking is elevated. The user should consider

stopping the run (Figure 5).

Figure 1. Tubing should be taut and centered in the channel while the pump head is closed. Gently sliding the

consumable sensor tray away from the pump head (white arrow) can ensure the tubing is taut during loading and

reloading.

Figure 2. Examples where the tubing is positioned too high (A) or low (B) in the channel of the pump.

The tubing should be centered vertically with respect to the roller.

A B

Figure 3. Properly loaded, the tube is centered in the channel without excess tubing through the pump head (A).

Approximately 3 mm of roller should be visible when the tube is centered (B).

A B

Figure 4. Normal tubing wear. The tubing lacks ridges, gouges, dents, or material loss. Discoloration and attening

are normal during peristaltic pumping operation.

Figure 5. In the rare occurrence that the tubing fails in a peristaltic pump, the failure is generally near the end of

the pumping channel out the out-ow side (A). If the presence of ssures, gouges, or cuts are observed (B), the risk

of leaking is elevated, and the user should consider stopping the run as a leak may occur.

Flow

Elevated

wear region

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Warranty/Disclaimer: Unless otherwise specied, all products are for research use or general laboratory use only.* Not intended for use in diagnostic

or therapeutic procedures. Not for use in humans. These products are not intended to mitigate the presence of microorganisms on surfaces or in the

environment, where such organisms can be deleterious to humans or the environment. Corning Life Sciences makes no claims regarding the performance

of these products for clinical or diagnostic applications. *For a listing of US medical devices, regulatory classications or specic information on claims,

visit www.corning.com/resources.

Corning’s products are not specically designed and tested for diagnostic testing. Many Corning products, though not specic for diagnostic testing, can be

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claims or statements that our products are approved for diagnostic testing either directly or indirectly. The customer is responsible for any testing, validation,

and/or regulatory submissions that may be required to support the safety and efcacy of their intended application.