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FocusJet Nebulizer
For
Thermo Scientific Dionex
Corona Veo (RS) Detectors
And
Vanquish VH-D20, VF-D20
Detectors
InstallationGuide
4820.8187Revision2.0a•December2017
thermoscientific
Copyright © 2016 Thermo Fisher Scientific Inc. All rights reserved.
The hardware descriptions in this manual revision refer to Thermo Scientific Dionex Corona Veo,
Corona Veo RS and Vanquish Charged Aerosol Detectors VH-D20 and VF-D20 detectors.
Trademarks
All trademarks are property of Thermo Fisher Scientific and its subsidiaries.
Thermo Fisher Scientific Inc. provides this document to its customers with a product purchase to
use in the product operation. The document is copyright protected; any reproduction of the
whole or any part of this document is strictly prohibited, except with the written authorization
of Thermo Fisher Scientific Inc.
This manual is provided "as is." The contents of this manual are subject to being changed,
without notice, in future revisions.
Thermo Fisher Scientific Inc. makes no representations that this document is complete,
accurate, or error-free. Thermo Fisher Scientific Inc. assumes no responsibility and will not be
liable for any errors, omissions, damage, or loss that might result from any use of this document,
even if the information in the document is followed properly.
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The Terms and Conditions of Sale shall govern all conflicting information between the two
documents.
Release history
Revision 2.0, released in April 2016
Revision 1.0, released in July 2013
Printed manual version only
Printed in Germany on 100% chlorine-free bleached, high-white paper that is produced in an
environmentally friendly process, leading to a paper profile of zero CO2 emissions.
Contents
FocusJet Nebulizer Installation Guide Page 3
Contents
1 Using this Manual ......................................................................... 4
1.1 About this Manual .................................................................................................. 4
1.2 Safety Symbols and Signal Words ........................................................................... 4
2 Installation .................................................................................... 5
2.1 Safety Guidelines for Installation ............................................................................ 5
2.2 Installing the Nebulizer ........................................................................................... 7
2.3 Gas Pressure Setting for the Nebulizer ................................................................. 12
1 • Using this Manual
Page 4 FocusJet Nebulizer Installation Guide
1 Using this Manual
1.1 About this Manual
This manual provides instructions for installing the FocusJet™ nebulizer
to Thermo Scientific™ Dionex™ Corona™ Veo™ and Corona Veo RS
detectors and Vanquish Charged Aerosol Detectors VH-D20 and VF-D20.
This guide is intended as a supplementary document to the Operating
Manual. Refer to the Operating Manual for the detector for general
safety information on the device, and the conventions used throughout
this manual regarding safety messages, notices and typography.
Keep these instructions with the Operating Manual for the detector for
quick reference.
1.2 Safety Symbols and Signal Words
This manual contains safety messages to prevent injury of the persons
using the detector. The safety symbols and signal words in this manual
include the following:
Always be aware of the safety information. Do not proceed until you
have fully understood the information and consider the consequences of
what you are doing.
CAUTION Indicates a hazardous situation that, if not avoided, could
result in minor or moderate injury.
WARNING Indicates a hazardous situation that, if not avoided, could
result in serious injury.
2 • Installation
FocusJet Nebulizer Installation Guide Page 5
2 Installation
This chapter describes how to install the FocusJet nebulizer to the
detector.
2.1 Safety Guidelines for Installation
Pay attention to the following safety guidelines:
CAUTION—Sharp Tip of Nebulizer Capillary
The capillary inside the nebulizer that protrudes from the nebulizer tip is
sharp and may be fragile. The nebulizer capillary can cause personal
injury and damage to the capillary. To avoid personal injury, always wear
safety glasses when handling the nebulizer. Do not touch the nebulizer
tip. Handle the nebulizer with care.
CAUTION—Escaping Gas
Gas can escape from open gas connections when the detector gas flow
and/or the gas supply is turned on. The escaping gas can pose a health
and safety risk.
Make sure that the detector gas flow and the gas supply are turned off
before you remove the nebulizer, disconnect the gas tubes or remove
the gas filter assembly from the detector.
Turn on the gas supply and detector gas flow only when the nebulizer is
installed, the components in the gas flow path are properly connected,
and the protective cover of the gas filter assembly is installed.
2 • Installation
Page 6 FocusJet Nebulizer Installation Guide
NOTICE—Sensitive Nebulizer
The nebulizer is highly sensitive to contamination and damage. Observe
the following safety notes:
• The nebulizer is highly sensitive to contamination. Even minute
particles on the nebulizer can lead to contamination and poor
detector performance. Always wear clean-room gloves when you
install or remove the nebulizer.
• The capillary inside the nebulizer may be fragile and subject to
mechanical vibrations during transport. If the nebulizer was
packaged separately, visually inspect the nebulizer surfaces and the
nebulizer tip prior to installation. For pictures of the nebulizer, see
the Preparations below.
• Operating the nebulizer with a gas pressure other than the pressure
specified for this nebulizer can cause a loss in performance of the
nebulizer and the detector. After installation of the nebulizer, set the
nebulizer gas pressure to the pressure that is specified for your
nebulizer. The nebulizer gas pressure is defined on the gas pressure
certificate that is shipped with the nebulizer.
2 • Installation
FocusJet Nebulizer Installation Guide Page 7
2.2 Installing the Nebulizer
Parts and additional items required
• Clean-room gloves (powder-free)
• FocusJet nebulizer with dedicated nebulizer gas pressure certificate
• Optional: Deionized water
Preparations
1. Wear the clean-room gloves.
2. If a nebulizer is installed in the detector
a) Remove the old nebulizer from the detector. Refer to the
instructions in the Operating Manual for the detector.
b) Make sure that detector operation is stopped, this includes:
♦ The detector has been flushed to remove any residues from
the flow paths.
♦ Pump flow, gas flow and gas supply to the detector are
turned off.
♦ The detector is turned off with its main power switch, and
the power cord is disconnected.
For instructions, refer to the Operating Manual for the detector.
3. Upon initial installation of the detector
Locate the nebulizer to be installed.
♦ Vanquish VH-/VF-D20 detectors:
The nebulizer is shipped in a foam insert behind the doors of the
VH-/VF-D20 detector. Remove the nebulizer from behind the
doors.
♦ Corona Veo/Veo RS detectors:
The nebulizer is shipped in a foam insert on the inner side of the
white cover on the Corona Veo (RS) detector. Take off the white
cover and remove the foam insert with the nebulizer from the
white cover.
2 • Installation
Page 8 FocusJet Nebulizer Installation Guide
4. Unpack the nebulizer carefully from the packaging. Locate the gas
pressure certificate for the nebulizer.
Keep the nebulizer packaging to have it available when transporting
the nebulizer.
Figure 1: Parts of the nebulizer
No. Description
1 Liquid flow inlet
2 Handle
3 Sealing bushing with sealing ring
4 Spray pipe
5 Nebulizer capillary on the tip of the spray pipe
5. Remove the protective tubing from the nebulizer spray pipe
carefully. Do not to touch the nebulizer tip with the protective
tubing, as it can damage the tip.
Keep the protective tubing to have it available when transporting
the nebulizer.
Figure 2: Nebulizer with protective tubing and plug on the flow inlet
2 • Installation
FocusJet Nebulizer Installation Guide Page 9
Follow these steps
1. If a dust seal plug is installed on the detector
Remove the dust seal plug from the opening for the nebulizer on the
interior front of the detector.
Figure 3: Dust seal plug installed in the nebulizer opening
2. Insert the nebulizer in the opening in the front panel of the detector.
Observe the following:
TIP To facilitate inserting the nebulizer in the nebulizer opening,
moisten the sealing ring on the sealing bushing with deionized
water.
♦ The nebulizer tip must point to the opening in the middle of the
nebulizer opening. Avoid the nebulizer tip from touching the
sides of the nebulizer opening, as this can damage the tip.
2 • Installation
Page 10 FocusJet Nebulizer Installation Guide
♦ Mind the correct orientation of the nebulizer: The gripping sides
of the nebulizer are on the top and bottom side of the handle.
The protruding sides for attachment are on the left and right
side of the handle. See the picture below.
Figure 4: Correct orientation of the nebulizer for installation
3. Push the nebulizer into the opening until the spray pipe and sealing
bushing are completely in the opening. The nebulizer handle must
lie flush against the nebulizer opening.
Figure 5: Completely inserting the nebulizer
No. Description No. Description
1 Opening for the nebulizer on the
interior panel of the detector
2 Spray pipe
3 Sealing ring in the sealing bushing
No. Description
1 Opening in the middle of
the nebulizer opening
2 Gripping sides on top and
bottom handle side
3 Protruding sides on left
and right handle side
2 • Installation
FocusJet Nebulizer Installation Guide Page 11
4. Turn the nebulizer by 90 degrees clockwise in the opening to lock
the nebulizer. Check that the protruding sides on the nebulizer
arrest behind the two locks of the opening and lie against the
alignment pin.
Figure 6: Locking the nebulizer in the detector
No. Description
1 Locks on the nebulizer opening
2 Alignment pin
5. Set up the flow connections to the detector. Follow the instructions
in the Operating Manual for the detector.
6. Set the nebulizer gas pressure. See section 2.3, page 12.
2 • Installation
Page 12 FocusJet Nebulizer Installation Guide
2.3 Gas Pressure Setting for the Nebulizer
NOTICE Operating the nebulizer with a gas pressure other than the
pressure specified for this nebulizer can cause a loss in performance of
the nebulizer and the detector. After installation of the nebulizer, set the
nebulizer gas pressure to the pressure that is specified for your
nebulizer. The nebulizer gas pressure is defined on the gas pressure
certificate that is shipped with the nebulizer.
Before operating the detector, verify and if required adjust the gas
pressure setting for the nebulizer. The nebulizer must only be operated
with the gas pressure setting stated on the certificate that was shipped
with the nebulizer.
Preparations
1. Connect the power cord to the power-inlet connector on the
detector.
2. Turn on the detector with its main power switch.
Follow these steps
1. Check if the gas pressure on the nebulizer certificate corresponds to
the pressure set in the detector. For instructions, refer to the
Operating Manual for the detector.
♦ If the gas pressure corresponds to the gas pressure on the
nebulizer certificate, continue with step 3, page 13.
♦ If the gas pressure deviates from the pressure on the nebulizer
certificate, adjust the gas pressure. See next step.
2. Adjust the nebulizer gas pressure to the pressure that is specified on
the nebulizer certificate. Monitor the gas pressure as it reaches the
setpoint.
♦ Vanquish VH-/VF-D20 detectors:
In Chromeleon, on the Command window for the detector, set
the nebulizer gas pressure (Gas Regulator Pressure Nominal).
♦ Corona Veo RS detectors:
On the detector display, navigate to the Gas Regulator screen.
Set nebulizer gas pressure under Setpoint.
2 • Installation
FocusJet Nebulizer Installation Guide Page 13
♦ Corona Veo detectors:
On the detector display, navigate to the Gas Regulator screen.
On the rear side of the detector, adjust the nebulizer gas
pressure using the gas regulator knob.
For details on adjusting the nebulizer gas pressure, refer to the
Operating Manual for the respective detector.
3. Turn on the gas flow. Refer to the Operating Manual for the
detector.
4. If required by internal regulatory department
TIP Instrument requalification is typically unnecessary after
replacing the nebulizer, but may be required by your regulatory
department.
a) Perform the detector-specific Performance Qualification (PQ)
tests using the Chromeleon software. For details, refer to the
Operational and Performance Qualifications manual.
b) VH-/VF-D20 detectors only: If PQ is performed, in Chromeleon,
execute the QualificationDone command. The command is
listed under CAD_Wellness.
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