Thermo Fisher Scientific FocusJet Nebulizer Installation guide

Brand: Thermo Fisher Scientific

Model: FocusJet Nebulizer

Type: Installation guide



FocusJet Nebulizer

For

Thermo Scientific Dionex

Corona Veo (RS) Detectors

And

Vanquish VH-D20, VF-D20

Detectors

InstallationGuide

4820.8187Revision2.0a•December2017



thermoscientific

The hardware descriptions in this manual revision refer to Thermo Scientific Dionex Corona Veo,

Corona Veo RS and Vanquish Charged Aerosol Detectors VH-D20 and VF-D20 detectors.

Trademarks

All trademarks are property of Thermo Fisher Scientific and its subsidiaries.

Thermo Fisher Scientific Inc. provides this document to its customers with a product purchase to

use in the product operation. The document is copyright protected; any reproduction of the

whole or any part of this document is strictly prohibited, except with the written authorization

of Thermo Fisher Scientific Inc.

This manual is provided "as is." The contents of this manual are subject to being changed,

without notice, in future revisions.

Thermo Fisher Scientific Inc. makes no representations that this document is complete,

accurate, or error-free. Thermo Fisher Scientific Inc. assumes no responsibility and will not be

liable for any errors, omissions, damage, or loss that might result from any use of this document,

even if the information in the document is followed properly.

This document is not part of any sales contract between Thermo Fisher Scientific Inc. and a

purchaser. This document shall in no way govern or modify any Terms and Conditions of Sale.

The Terms and Conditions of Sale shall govern all conflicting information between the two

documents.

Release history

Revision 2.0, released in April 2016

Revision 1.0, released in July 2013

Printed manual version only

Printed in Germany on 100% chlorine-free bleached, high-white paper that is produced in an

environmentally friendly process, leading to a paper profile of zero CO2 emissions.

Contents

FocusJet Nebulizer Installation Guide Page 3

Contents

1 Using this Manual ......................................................................... 4

1.1 About this Manual .................................................................................................. 4

1.2 Safety Symbols and Signal Words ........................................................................... 4

2 Installation .................................................................................... 5

2.1 Safety Guidelines for Installation ............................................................................ 5

2.2 Installing the Nebulizer ........................................................................................... 7

2.3 Gas Pressure Setting for the Nebulizer ................................................................. 12

1 • Using this Manual

Page 4 FocusJet Nebulizer Installation Guide

1 Using this Manual

1.1 About this Manual

This manual provides instructions for installing the FocusJet™ nebulizer

to Thermo Scientific™ Dionex™ Corona™ Veo™ and Corona Veo RS

detectors and Vanquish Charged Aerosol Detectors VH-D20 and VF-D20.

This guide is intended as a supplementary document to the Operating

Manual. Refer to the Operating Manual for the detector for general

safety information on the device, and the conventions used throughout

this manual regarding safety messages, notices and typography.

Keep these instructions with the Operating Manual for the detector for

quick reference.

1.2 Safety Symbols and Signal Words

This manual contains safety messages to prevent injury of the persons

using the detector. The safety symbols and signal words in this manual

include the following:

Always be aware of the safety information. Do not proceed until you

have fully understood the information and consider the consequences of

what you are doing.

CAUTION Indicates a hazardous situation that, if not avoided, could

result in minor or moderate injury.

WARNING Indicates a hazardous situation that, if not avoided, could

result in serious injury.

2 • Installation

FocusJet Nebulizer Installation Guide Page 5

2 Installation

This chapter describes how to install the FocusJet nebulizer to the

detector.

2.1 Safety Guidelines for Installation

Pay attention to the following safety guidelines:

CAUTION—Sharp Tip of Nebulizer Capillary

The capillary inside the nebulizer that protrudes from the nebulizer tip is

sharp and may be fragile. The nebulizer capillary can cause personal

injury and damage to the capillary. To avoid personal injury, always wear

safety glasses when handling the nebulizer. Do not touch the nebulizer

tip. Handle the nebulizer with care.

CAUTION—Escaping Gas

Gas can escape from open gas connections when the detector gas flow

and/or the gas supply is turned on. The escaping gas can pose a health

and safety risk.

Make sure that the detector gas flow and the gas supply are turned off

before you remove the nebulizer, disconnect the gas tubes or remove

the gas filter assembly from the detector.

Turn on the gas supply and detector gas flow only when the nebulizer is

installed, the components in the gas flow path are properly connected,

and the protective cover of the gas filter assembly is installed.

2 • Installation

Page 6 FocusJet Nebulizer Installation Guide

NOTICE—Sensitive Nebulizer

The nebulizer is highly sensitive to contamination and damage. Observe

the following safety notes:

• The nebulizer is highly sensitive to contamination. Even minute

particles on the nebulizer can lead to contamination and poor

detector performance. Always wear clean-room gloves when you

install or remove the nebulizer.

• The capillary inside the nebulizer may be fragile and subject to

mechanical vibrations during transport. If the nebulizer was

packaged separately, visually inspect the nebulizer surfaces and the

nebulizer tip prior to installation. For pictures of the nebulizer, see

the Preparations below.

• Operating the nebulizer with a gas pressure other than the pressure

specified for this nebulizer can cause a loss in performance of the

nebulizer and the detector. After installation of the nebulizer, set the

nebulizer gas pressure to the pressure that is specified for your

nebulizer. The nebulizer gas pressure is defined on the gas pressure

certificate that is shipped with the nebulizer.

2 • Installation

FocusJet Nebulizer Installation Guide Page 7

2.2 Installing the Nebulizer

Parts and additional items required

• Clean-room gloves (powder-free)

• FocusJet nebulizer with dedicated nebulizer gas pressure certificate

• Optional: Deionized water

Preparations

1. Wear the clean-room gloves.

2. If a nebulizer is installed in the detector

a) Remove the old nebulizer from the detector. Refer to the

instructions in the Operating Manual for the detector.

b) Make sure that detector operation is stopped, this includes:

♦ The detector has been flushed to remove any residues from

the flow paths.

♦ Pump flow, gas flow and gas supply to the detector are

turned off.

♦ The detector is turned off with its main power switch, and

the power cord is disconnected.

For instructions, refer to the Operating Manual for the detector.

3. Upon initial installation of the detector

Locate the nebulizer to be installed.

♦ Vanquish VH-/VF-D20 detectors:

The nebulizer is shipped in a foam insert behind the doors of the

VH-/VF-D20 detector. Remove the nebulizer from behind the

doors.

♦ Corona Veo/Veo RS detectors:

The nebulizer is shipped in a foam insert on the inner side of the

white cover on the Corona Veo (RS) detector. Take off the white

cover and remove the foam insert with the nebulizer from the

white cover.

2 • Installation

Page 8 FocusJet Nebulizer Installation Guide

4. Unpack the nebulizer carefully from the packaging. Locate the gas

pressure certificate for the nebulizer.

Keep the nebulizer packaging to have it available when transporting

the nebulizer.

Figure 1: Parts of the nebulizer

No. Description

1 Liquid flow inlet

2 Handle

3 Sealing bushing with sealing ring

4 Spray pipe

5 Nebulizer capillary on the tip of the spray pipe

5. Remove the protective tubing from the nebulizer spray pipe

carefully. Do not to touch the nebulizer tip with the protective

tubing, as it can damage the tip.

Keep the protective tubing to have it available when transporting

the nebulizer.

Figure 2: Nebulizer with protective tubing and plug on the flow inlet

2 • Installation

FocusJet Nebulizer Installation Guide Page 9

Follow these steps

1. If a dust seal plug is installed on the detector

Remove the dust seal plug from the opening for the nebulizer on the

interior front of the detector.

Figure 3: Dust seal plug installed in the nebulizer opening

2. Insert the nebulizer in the opening in the front panel of the detector.

Observe the following:

TIP To facilitate inserting the nebulizer in the nebulizer opening,

moisten the sealing ring on the sealing bushing with deionized

water.

♦ The nebulizer tip must point to the opening in the middle of the

nebulizer opening. Avoid the nebulizer tip from touching the

sides of the nebulizer opening, as this can damage the tip.

2 • Installation

Page 10 FocusJet Nebulizer Installation Guide

♦ Mind the correct orientation of the nebulizer: The gripping sides

of the nebulizer are on the top and bottom side of the handle.

The protruding sides for attachment are on the left and right

side of the handle. See the picture below.

Figure 4: Correct orientation of the nebulizer for installation

3. Push the nebulizer into the opening until the spray pipe and sealing

bushing are completely in the opening. The nebulizer handle must

lie flush against the nebulizer opening.

Figure 5: Completely inserting the nebulizer

No. Description No. Description

1 Opening for the nebulizer on the

interior panel of the detector

2 Spray pipe

3 Sealing ring in the sealing bushing

No. Description

1 Opening in the middle of

the nebulizer opening

2 Gripping sides on top and

bottom handle side

3 Protruding sides on left

and right handle side

2 • Installation

FocusJet Nebulizer Installation Guide Page 11

4. Turn the nebulizer by 90 degrees clockwise in the opening to lock

the nebulizer. Check that the protruding sides on the nebulizer

arrest behind the two locks of the opening and lie against the

alignment pin.

Figure 6: Locking the nebulizer in the detector

No. Description

1 Locks on the nebulizer opening

2 Alignment pin

5. Set up the flow connections to the detector. Follow the instructions

in the Operating Manual for the detector.

6. Set the nebulizer gas pressure. See section 2.3, page 12.

2 • Installation

Page 12 FocusJet Nebulizer Installation Guide

2.3 Gas Pressure Setting for the Nebulizer

NOTICE Operating the nebulizer with a gas pressure other than the

pressure specified for this nebulizer can cause a loss in performance of

the nebulizer and the detector. After installation of the nebulizer, set the

nebulizer gas pressure to the pressure that is specified for your

nebulizer. The nebulizer gas pressure is defined on the gas pressure

certificate that is shipped with the nebulizer.

Before operating the detector, verify and if required adjust the gas

pressure setting for the nebulizer. The nebulizer must only be operated

with the gas pressure setting stated on the certificate that was shipped

with the nebulizer.

Preparations

1. Connect the power cord to the power-inlet connector on the

detector.

2. Turn on the detector with its main power switch.

Follow these steps

1. Check if the gas pressure on the nebulizer certificate corresponds to

the pressure set in the detector. For instructions, refer to the

Operating Manual for the detector.

♦ If the gas pressure corresponds to the gas pressure on the

nebulizer certificate, continue with step 3, page 13.

♦ If the gas pressure deviates from the pressure on the nebulizer

certificate, adjust the gas pressure. See next step.

2. Adjust the nebulizer gas pressure to the pressure that is specified on

the nebulizer certificate. Monitor the gas pressure as it reaches the

setpoint.

♦ Vanquish VH-/VF-D20 detectors:

In Chromeleon, on the Command window for the detector, set

the nebulizer gas pressure (Gas Regulator Pressure Nominal).

♦ Corona Veo RS detectors:

On the detector display, navigate to the Gas Regulator screen.

Set nebulizer gas pressure under Setpoint.

2 • Installation

FocusJet Nebulizer Installation Guide Page 13

♦ Corona Veo detectors:

On the detector display, navigate to the Gas Regulator screen.

On the rear side of the detector, adjust the nebulizer gas

pressure using the gas regulator knob.

For details on adjusting the nebulizer gas pressure, refer to the

Operating Manual for the respective detector.

3. Turn on the gas flow. Refer to the Operating Manual for the

detector.

4. If required by internal regulatory department

TIP Instrument requalification is typically unnecessary after

replacing the nebulizer, but may be required by your regulatory

department.

a) Perform the detector-specific Performance Qualification (PQ)

tests using the Chromeleon software. For details, refer to the

Operational and Performance Qualifications manual.

b) VH-/VF-D20 detectors only: If PQ is performed, in Chromeleon,

execute the QualificationDone command. The command is

listed under CAD_Wellness.

Thermo Fisher Scientific Inc.

168 Third Avenue

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Massachusetts 02451

USA

www.thermofisher.com

Thermo Fisher Scientific FocusJet Nebulizer Installation guide

Brand: Thermo Fisher Scientific

Model: FocusJet Nebulizer

Type: Installation guide

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Thermo Fisher Scientific FocusJet Nebulizer Installation guide

Thermo Fisher Scientific FocusJet Nebulizer Installation guide

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